For patients living with musculoskeletal conditions, participating in clinical trials can be challenging. Limited mobility due to pain, stiffness, or joint deterioration often makes traveling to clinical sites a significant obstacle. Musculoskeletal conditions often co-exist with other health issues, further complicating logistics and contributing to the burden of participation. During this study, 48 patients were referred to Home Trial Support (HTS), addressing these challenges by offering a solution that reduces the need for travel and accommodates patients’ individual needs.